Publications by authors named "A Nasrolahi"
Prevalence of plasmid-mediated quinolone resistance genes and biofilm formation in different species of quinolone-resistant clinical Shigella isolates: a cross-sectional study.
Eur J Med Res
August 2024
Article Synopsis
- The study aimed to investigate plasmid-mediated quinolone resistance (PMQR) genes and biofilm formation in Shigella isolates that are resistant to quinolones, using clinical samples from children under 10 years old.
- Researchers collected stool samples from 150 patients, identifying 95 Shigella isolates primarily as S. sonnei and S. flexneri, with a notable percentage showing multidrug resistance.
- The presence of PMQR genes was significant, especially qnrS and qnrA, and biofilm formation was also assessed, indicating a complex challenge for treatment options in these resistant strains.
Coral reefs are highly biodiverse ecosystems, enriched by a range of biofouling species. Temporal variations in biofouling can affect ecosystem stability, but these diverse coral-associated communities remain underexplored in some regions. In the present study, biofouling assemblages of coral reefs in the Chabahar Bay were investigated during a summer monsoon at three deployment periods.
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- * The lncRNA X-inactive specific transcript (XIST) is particularly important as it is downregulated early in ischemic stroke but increases later, influencing the disease through its interactions with various miRNAs and transcription factors.
- * This review examines the role of XIST in ischemic stroke, aiming to provide insights into its mechanisms and explore potential new targets for treatment.
Long non-coding RNAs (lncRNAs) are non-protein coding transcripts that are longer than 200 nucleotides in length. LncRNAs are implicated in gene expression at the transcriptional, translational, and epigenetic levels, and thereby impact different cellular processes including cell proliferation, migration, apoptosis, angiogenesis, and immune response. In recent years, numerous studies have demonstrated the significant contribution of lncRNAs to the pathogenesis and progression of various diseases, such as stroke, heart disease, and cancer.
View Article and Find Full Text PDFLeukemia is a malignancy in the blood that develops from the lymphatic system and bone marrow. Although various treatment options have been used for different types of leukemia, understanding the molecular pathways involved in the development and progression of leukemia is necessary. Recent studies showed that leukemia stem cells (LSCs) play essential roles in the pathogenesis of leukemia by targeting several signaling pathways, including Notch, Wnt, Hedgehog, and STAT3.
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