Publications by authors named "A Nashat"
Purpose: To create a computer-aided prediction (CAP) system to predict Wilms tumor (WT) responsiveness to preoperative chemotherapy (PC) using pre-therapy contrast-enhanced computed tomography (CECT).
Materials And Methods: A single-center database was reviewed for children <18 years diagnosed with WT and received PC between 2001 and 2021. Patients were excluded if pre- and post-PC CECT were not retrievable.
Article Synopsis
- Wilms' tumor is the most common kidney cancer in children and has a serious risk of recurrence; its treatment often involves surgery, chemotherapy, and sometimes radiation.
- The study aimed to create a computer-aided prediction system to assess how Wilms' tumors would respond to preoperative chemotherapy, involving imaging analysis of 63 patients.
- Using advanced imaging techniques and machine learning, the system achieved high accuracy (95.24%) in predicting treatment responses, which could help tailor individualized treatment plans for patients.
The ziprasidone analogue lurasidone is approved for the treatment of schizophrenia and bipolar disorder for adults and children older than 10 years. Small studies and case reports suggest lurasidone overdose is not generally associated with major adverse effects, but no large sample has been published. To describe intentional lurasidone overdoses reported to poison centers.
View Article and Find Full Text PDFBackground: Occlusive treatments are a mainstay in atopic dermatitis (AD) management but may not be well tolerated or lack compliance. A comfortable, semiocclusive, artificial skin barrier that is well tolerated, provides protection, and reduces water loss is needed.
Objective: To evaluate the potential tolerability and therapeutic benefits of a crosslinked polymer layer (XPL) in adults with AD.