Fluorescence-based photoinduced electron transfer (PET) has garnered significant attention in the molecular recognition field in recent years because of its unique and desirable photophysical properties. Recent advancements in PET-based chemosensors have demonstrated their potential for real-time monitoring of pollutants such as heavy metals, pesticides, and organic contaminants in various environmental matrices. This review emphasizes the recent advancements in fluorogenic and chromogenic PET-based chemosensors based on Anthracene, Imidazole, Indole, Pyrrole, Thiazole, Naphthalene, Quinoline, Calix[4]arene, Fluorescein, Quantum Dots, Schiff base compounds and also focusing on their molecular design, sensing mechanisms, and photophysical properties reported from the year 2011 to 2024.
View Article and Find Full Text PDFBackground: Skeletal muscle mass is determined predominantly by feeding-induced and activity-induced fluctuations in muscle protein synthesis (MPS). Older individuals display a diminished MPS response to protein ingestion, referred to as age-related anabolic resistance, which contributes to the progression of age-related muscle loss known as sarcopenia.
Objectives: We aimed to determine the impact of consuming higher-quality compared with lower-quality protein supplements above the recommended dietary allowance (RDA) on integrated MPS rates.
We report a case of fulminant COVID-19-related myocarditis requiring venoarterial extracorporeal membrane oxygenation where the use of an ultrasound-enhancing agent demonstrated a previously undescribed echocardiographic finding, the "lightbulb" sign. This sign potentially represents a new area for the use of an ultrasound enhancing agent in the echocardiographic diagnosis of myocarditis.
View Article and Find Full Text PDFHeart Rhythm O2
December 2022
Background: Delivery of electrophysiology (EP) care in developing nations and underserviced populations faces many hurdles, including the lack of local expertise and knowledge creation. The West Indies has experienced a paucity of local EP expertise. The University of Toronto has undertaken a unique collaborative educational effort with the University of the West Indies.
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