Publications by authors named "A Namachivayam"

Article Synopsis
  • This study aims to validate the International Study Group of Pancreatic Surgery (ISGPS) classification for predicting clinically relevant pancreatic fistula (CRPF) specifically in patients with periampullary tumors (P-amps).
  • The authors tested the ISGPS model on data from 1,422 patients and found a CRPF rate of 22.2%, which is higher (25.8%) for P-amps, revealing the need for a tailored prediction model.
  • By optimizing the classification for P-amps, the adjusted ISGPS showed improved predictive ability (AUC=0.672) compared to the original model, highlighting the need for further research with larger, multicenter studies.
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Ethanol (EtOH) is most widely used in alcoholic beverages to prepare alcohol. As EtOH is mainly metabolised in the liver, the excessive consumption of EtOH forms a primary toxic metabolic product called acetaldehyde, as the gradual increase in acetaldehyde leads to liver injury, as reported. Lauric acid (LA) is rich in antioxidant, antifungal, antibacterial, anticancer, and antiviral properties.

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Cancer is a major threat to human life around the globe, and the discovery of novel biomolecules continue to be an urgent therapeutic need that is still unmet. Precision medicine relies on targeted therapeutic strategies. Researchers are better equipped to develop therapies that target proteins as they understand more about the genetic alterations and molecules that cause progression of cancer.

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