Effects of air exposure time on tissue morphology, energy metabolism, and non-specific immunity of the juvenile Chinese mitten crab, Eriocheir sinensis.

This study investigated the effect of aerial exposure duration (0, 24, 48, and 72 h) on the juvenile Chinese mitten crab, Eriocheir sinensis. The effects on histological structure, energy metabolism, non-specific immunity, and expression of cytochrome P450 (CYP2) and protein kinase B (AKT) genes in the anterior gill and hepatopancreas were analyzed. Longer durations of air exposure led to loss of anterior gill filament shape, and enlargement and deformation of the hepatopancreatic tubules with vacuolization.

Lateral Retrocanthal Orbital Decompression for Children With Thyroid Eye Disease: A Canthus-sparing Approach.

Thyroid eye disease (TED) is one of the most common causes of proptosis in children. The traditional surgical approach to manage disfiguring proptosis associated with TED is orbital decompression surgery, which is often accomplished via lateral wall decompression through canthotomy and cantholysis. However, this technique can result in lateral canthus scarring and migration.

Transcription factor networks and novel immune biomarkers reveal key prognostic and therapeutic insights in ovarian cancer.

Background: Understanding the tumor microenvironment (TME) is essential for the advancement of immunotherapy for ovarian cancer (OC). Nonetheless, predicting transcription factor (TF) regulation from the TME using single-cell RNA sequencing (scRNA-seq) data is challenging.

Methods: The OC scRNA-seq data were analyzed with a specialized scRNA-seq transcriptome analysis application.

Connecting Underrepresented Medical Students to Resources and Role Models in Orthopaedic Surgery: A Virtual Diversity, Equity, Inclusion, and Accessibility Summit.

Introduction: Limited access to resources and stereotypes about orthopaedic surgeons may contribute to the low percentage of women and people of underrepresented in medicine (URiM) backgrounds in orthopaedic surgery. Several organizations have created resources to address these barriers, but medical students are unlikely to be exposed to the initiatives through traditional curricula. The purpose of this study was to (1) evaluate the ability of a 1-day virtual Diversity, Equity, Inclusion, and Accessibility (DEIA) summit to effectively reach URiM medical students, (2) increase medical students' knowledge of DEIA resources, and (3) augment the perception of diverse backgrounds in orthopaedic surgery.

Mechanistic Insights into Regioselectivity and Its Evolution in On-Surface Polymerization.

Surface-catalyzed polymerization is crucial in both chemical science and industrial manufacturing, yet achieving regioselective radical polymerization on the surface remains challenging. Here, we demonstrate the regioselective Ullmann polymerization of nonsymmetrical 2,8-dibromoquinoline (DBQ) on an Au(111) surface. By combining scanning tunneling microscopy, density functional theory calculations, and kinetic modeling, we reveal the regioselectivity and its evolution with surface temperature at the molecular level.