Publications by authors named "A N Verma"

Study Design: Systematic review and meta analysis.

Objective: To assess the safety and efficacy of staged versus same-day spinal fusion surgeries in Adult spinal deformity (ASD).

Background: ASD surgeries are associated with high complication rates, ranging from 10% to 40%.

View Article and Find Full Text PDF

Aims And Background: Carbapenem-resistant (CRAb), a major public health threat, causes severe infections in Intensive Care Unit (ICU) patients. It resists β-lactam antibiotics through mechanisms like New Delhi metallo-beta-lactamase (NDM).

Materials And Methods: In ICU patients, 69 species were isolated from 86 non-fermenting Gram-negative bacilli.

View Article and Find Full Text PDF

Background: Depression among the elderly is a growing public health concern, especially in India. This study aimed to investigate the predictive validity of physiological, psychological, and functional health factors in classifying the level of depressive symptoms among the elderly using the extreme gradient boosting (XGBoost) technique. Additionally, we compared the performance of models trained on original and resampled data.

View Article and Find Full Text PDF

According to the Humane Society, 25 to 40 percent of pet dogs in the United States are adopted from animal shelters. Shelter dogs can harbor bacterial, viral, fungal, and protozoal pathogens, posing risks to canine and human health. These bacterial pathogens may also carry antibiotic resistance genes (ARGs), serving as a reservoir for antimicrobial resistance (AMR) transmission.

View Article and Find Full Text PDF
Article Synopsis
  • This study focuses on PRT543, a new oral medication designed to inhibit PRMT5, an enzyme implicated in the growth of certain blood cancers.
  • It specifically investigates the effects of PRT543 in patients suffering from advanced myeloid malignancies that have mutations in splicing factors, which are crucial for proper gene expression and can contribute to cancer progression.
  • The early Phase Ib trial aims to assess the safety, tolerability, and initial effectiveness of PRT543 in these patients, providing groundwork for potential future treatments.
View Article and Find Full Text PDF