Publications by authors named "A N Timofeeva"
Despite the increasing number of placenta accreta spectrum (PAS) cases in recent years, its impact on neonatal outcomes and respiratory morbidity, as well as the underlying pathogenetic mechanism, has not yet been extensively studied. Moreover, no study has yet demonstrated the effectiveness of antenatal corticosteroid therapy (CT) for the prevention of respiratory distress syndrome (RDS) in newborns of mothers with PAS at the molecular level. In this regard, microRNA (miRNA) profiling by small RNA deep sequencing and quantitative real-time PCR was performed on 160 blood plasma samples from preterm infants (gestational age: 33-36 weeks) and their mothers who had been diagnosed with or without PAS depending on the timing of the antenatal RDS prophylaxis.
View Article and Find Full Text PDFDespite prevention strategies, cervical cancer remains a significant public health issue. Human papillomavirus plays a critical role in its development, and early detection is vital to improve patient outcomes. The incidence of cervical cancer is projected to rise, necessitating better diagnostic tools.
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- * It highlights the importance of microglial plasticity and the microenvironment in influencing their polarization pathways, which can lead to either pro-inflammatory or anti-inflammatory responses post-injury.
- * The review provides insights on microglia activation, migration, and their effects on neighboring cells like neurons, astrocytes, and oligodendrocytes, which could help scientists develop better treatment strategies for CNS injuries.
Article Synopsis
- A large-scale study on antibiotic resistance in farm animal feces across Russia analyzed 6,578 samples from 13 regions, with contributions from citizen scientists, especially college students.
- The research utilized microbiological methods to test bacteria's sensitivity to antibiotics and molecular techniques to identify resistance genes, revealing significant regional variations in antibiotic resistance among the samples.
- Findings showed that while some regions had high sensitivity to antibiotics, others exhibited alarming levels of resistance, potentially due to farming practices promoting such resistance.