Publications by authors named "A N Synchuk"

The study was undertaken to examine central hemodynamic and carbohydrate metabolic parameters in patients with coronary heart disease (with or without signs of chronic heart failure, Stages I and IIA). The changes in carbohydrate metabolism in CHD patients were detected earlier than those in central hemodynamics. In patients with Stage I heart failure, who had normal resting hemodynamic parameters, metabolic parameters were indicative of abnormalities in carbohydrate metabolism: there was a reduction in carbohydrate tolerance and red blood cell release of insulin in response to glucose load and an increase in blood immunoreactive insulin, erythrocytic glucose-6-phosphate dehydrogenase activity and greater adrenalin- and insulin-containing erythrocytes.

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A study is presented of the central hemodynamics, renal function and water-salt metabolism in 42 patients with ischemic heart disease and chronic circulatory insufficiency (grades I and II) and revealed a deterioration of these indices in this categories of patients manifested in a retention of sodium, deterioration of central hemodynamics after increase of venous inflow.

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Indices of hemodynamics, some renal functions and mechanisms of their regulation were studied in 29 patients with ischemic heart disease and chronic circulatory insufficiency (grade IIA) and in 27 healthy persons under load conditions. Indices of central hemodynamics and renal function deteriorated in the patients after increase of preloads while there were no essential changes of the activity of renin-angiotensin-aldosteron activity.

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