Publications by authors named "A N Steele"
International web-based survey of patients with non-hydrocephalic symptomatic pineal cysts.
Acta Neurochir (Wien)
December 2024
Objectives: To report the results of an international patient-reported survey that adds to the growing body of evidence surrounding the role of surgery in the management of a subset of patients with non-hydrocephalic symptomatic pineal cyst.
Design: An international web-based survey of health outcomes in patients with nhSPC.
Subjects: All survey participants who self-reported a diagnosis of symptomatic pineal cyst without hydrocephalus after radiological imaging.
Purpose: The purpose of this study is to develop an evidence-based algorithm for the management of symptomatic bipartite patella in the pediatric and adolescent population based on a systemic review of the published literature.
Methods: A systematic review of the literature was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines on PubMed and Embase, selecting for studies discussing the management of symptomatic bipartite patella.
Results: Five studies met criteria, involving 315 knees (314 patients, average age 15.
High-energy-density materials (HEDMs) are crucial in various applications, from energy storage to defense technologies. Transition metal polynitrides are promising candidates for HEDMs. Using single-crystal synchrotron X-ray diffraction, we investigated the crystal structures of niobium nitride, specifically NbN and NbN, under high-pressure conditions of up to 86 GPa.
View Article and Find Full Text PDFThe rover explored the region between the orbitally defined phyllosilicate-bearing Glen Torridon trough and the overlying layered sulfate-bearing unit, called the "clay-sulfate transition region." Samples were drilled from the top of the fluviolacustrine Glasgow member of the Carolyn Shoemaker formation (CSf) to the eolian Contigo member of the Mirador formation (MIf) to assess in situ mineralogical changes with stratigraphic position. The Sample Analysis at Mars-Evolved Gas Analysis (SAM-EGA) instrument analyzed drilled samples within this region to constrain their volatile chemistry and mineralogy.
View Article and Find Full Text PDFArticle Synopsis
- - Polyketide synthases (PKSs) typically produce a variety of natural products but rarely include sulfur-containing compounds, leading to an investigation of thiocysteine lyase (SH) domains involved in biosynthesizing the leinamycin family, like LnmJ-SH and GnmT-SH.
- - A detailed study was conducted using a 1.8 Å resolution crystal structure of GnmT-SH, alongside synthesized substrate mimics and various techniques such as bioinformatics and mutagenesis, to understand the acyl carrier protein (ACP)-tethered substrate interactions and specificity of the SH domains.
- - The research highlights evolutionary modifications in protein structures that allow for the accommodation of larger ACP-t