Publications by authors named "A N Srour"
Endocytosis is a prominent mechanism for SARS-CoV-2 entry into host cells. Upon internalization into early endosomes (EEs), the virus is transported to late endosomes (LEs), where acidic conditions facilitate spike protein processing and viral genome release. Dynein and kinesin motors drive EE transport along microtubules; dynein moves EEs to the perinuclear region, while kinesins direct them towards the plasma membrane, creating a tug-of-war over the direction of transport.
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- * The new compounds were tested in the lab against various cancer cell lines and showed promising results, particularly compounds 8a and 8b, which had higher anticancer activity compared to the standard drug, erlotinib.
- * Compound 8a also showed effective inhibition of specific cancer-related proteins (EGFR and VEGFR-2), and additional computational studies provided insights into the compounds’ properties and how they might behave in the body.
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- Olecranon bursitis mainly impacts men aged 30 to 60 and can be acute or chronic in nature.
- Treatment for acute cases is usually simple, but chronic cases can be more difficult to manage.
- The publication presents a rare case of bilateral chronic olecranon bursitis and explores the reasoning behind selecting the most effective treatment option.
Design and synthesis of a series of 5-benzylidene(thio)barbiturates . Evaluation of the inhibitory activity of the new chemical entities on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) using Donepezil as the standard reference. Compound emerged as the most potent AChE inhibitor (IC = 9.
View Article and Find Full Text PDFAkin osteotomy is commonly used to correct hallux valgus interphalangeus (HVI) deformity. The preferred implant for fixation remains an area of debate, often influenced by the surgeon's inclinations and expertise. This review compares the outcomes of contemporary fixation methods utilized in Akin osteotomy.
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