Publications by authors named "A N Solopova"
Cerebral vein thrombosis is a rare, life-threatening condition that has now become more commonly diagnosed due to advancements in imaging techniques. Our purpose is to improve understanding of pathogenesis, diagnosis and pregnancy and IVF management in patients with a history of cerebral thrombosis. We present an overview of the modern tactics of anticoagulant therapy for cerebral thrombosis with a focus on pregnancy, the use of hormone therapy, and assisted reproductive technologies.
View Article and Find Full Text PDF[Impact of various rehabilitation programs on anxiety and depression after surgery of early-stage cervical cancer].
Vopr Kurortol Fizioter Lech Fiz Kult
November 2024
Article Synopsis
- Cervical cancer (CC) is increasingly common and presents significant health care challenges, even with HPV vaccination and screening efforts; there's a need to understand rehabilitation's role in reducing anxiety and depression post-surgery.
- A study involving 103 female CC patients compared two rehabilitation programs: one multicomponent and the other adhering to standard guidelines, assessing anxiety and depression levels pre-surgery and over 36 months post-op using the Hospital Anxiety and Depression Scale (HADS).
- Results showed that the multicomponent rehabilitation significantly decreased anxiety and depression more effectively than the standard program, highlighting its importance in recovery for early-stage CC patients.
Article Synopsis
- - Thrombotic microangiopathy (TMA) is a group of disorders where small blood vessel clotting causes organ damage, including conditions like thrombotic thrombocytopenic purpura (TTP) and hemolytic-uremic syndrome (HUS), each with unique causes and impacts on health.
- - In TMA, inflammation leads to endothelial damage and activates platelet and coagulation processes, often linked to low ADAMTS13 enzyme levels, particularly in cancer patients undergoing chemotherapy, which raises thrombotic risk by increasing the VWF/ADAMTS13 ratio.
- - Treatment focuses on diagnosing the specific cause and may include therapies to inhibit complement activation, supportive care, and plasmapheresis
Newborns are the most vulnerable patients for thrombosis development among all children, with critically ill and premature infants being in the highest risk group. The upward trend in the rate of neonatal thrombosis could be attributed to progress in the treatment of severe neonatal conditions and the increased survival in premature babies. There are physiological differences in the hemostatic system between neonates and adults.
View Article and Find Full Text PDFBackground: The current recommended therapy of obstetric antiphospholipid syndrome (APS) is a long-term anticoagulant therapy that affects the final event, namely, when the thrombosis has already occurred. Unfortunately, this schedule is not always effective and fails despite the correct risk stratification and an adequate adjusted dose.
Materials And Methods: From 2013 to 2020 we observed 217 women with antiphospholipid antibodies and obstetric morbidities who were treated with conventional treatment protocol (aspirin low doses ± LMWH).