Publications by authors named "A N Scholten"
Article Synopsis
- - This study examined how different interpretations of guidelines for outlining left-sided internal mammary lymph nodes (IMN) affect radiation exposure to nearby organs in breast cancer patients.
- - Using a cohort of 95 patients, it compared the NKI's interpretation with a deep learning model based on Danish guidelines, finding significant geometric and dosimetric differences, especially regarding heart dose.
- - The results indicated that variability in guideline interpretations can lead to higher heart radiation doses, highlighting the importance of establishing a uniform consensus in treatment practices to improve patient outcomes.
Background: Radiation associated angiosarcoma (RAAS) of the breast is a rare malignancy with poor survival. Optimal treatment strategies remain uncertain due to a lack of data, and vary between surgery alone and a combination of surgery with (neo)adjuvant chemotherapy (NACT) and/or re-irradiation. The aim of this study was to evaluate the potential benefit of taxane based NACT.
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- * An online survey conducted by the German Society for Public Health Services (DGÖG) gathered input from nearly 500 participants, primarily from local health departments, to prioritize 17 proposed guideline topics across six task areas.
- * All 17 topics were deemed high priority, with a strong emphasis on infection hygiene monitoring, medical expert assessment, and psychosocial emergency care, while additional topics such as health promotion and crisis management were also highlighted for future guideline development.
Purpose: This study aims to identify which breast cancer patients benefit from the routine use of FDG-PET/CT in a large cohort of patients scheduled for neoadjuvant systemic therapy (NST).
Methods: A total of 1337 breast cancer patients eligible for NST were identified from a retrospective database between 2011 and 2020 at a single tertiary care hospital. All patients underwent staging with FDG-PET/CT prior to NST.
Background: Nipple- or skin-sparing mastectomy and immediate implant-based breast reconstruction (IBR) is potentially associated with long-term unfavorable outcomes such as revision surgery and reconstruction failure. This large patient cohort study aimed to provide long-term data on the incidence of these outcomes and identify predictive risk factors.
Methods: Between 2012 and 2019 1,989 mastectomies with IBR were performed in 1,512 women in our institute.