Avirulence of a spontaneous Francisella tularensis subsp. mediasiatica prmA mutant.

Francisella tularensis, the causative agent of tularemia, is divided into three subspecies. Two of these, subspecies holarctica and tularensis, are highly pathogenic to humans and consequently relatively well studied. The third subspecies, mediasiatica, is rarely isolated and remains poorly studied.

Development and Properties of Subsp. 15 NIIEG Vaccine Strain without the Gene.

The genomic analysis of all subspecies , as found in Gen Bank NCBI, reveals the presence of genes encoding proteins like to the multifunctional RecBCD enzyme complex in and other bacteria. To date, the role of the gene in , which encodes the alpha chain of exonuclease V, in DNA metabolism processes, has not been studied either in vitro or in vivo. subsp.

Development of an immunoassay test system based on monoclonal antybodies and immunomagnetic particles for the detection of F. tularensis cells.

Tularemia is an especially dangerous infection caused by the gram-negative bacterium Francisella tularensis. It belongs to natural focal infections, and therefore is under continuous control by quarantine services. When carrying out their activities they use a whole range of diagnostic tools.

The Comparative Virulence of Subsp. for Vaccinated Laboratory Animals.

Tularemia is a severe infectious disease caused by the Gram-negative bacteria . There are four subspecies of : , , and , which differ in their virulence and geographic distribution. One of them, subsp.