Publications by authors named "A N Malaviya"
Article Synopsis
- - A woman in her 50s experienced a severe headache, collapsed, and was diagnosed with an acute subdural hemorrhage that needed surgery; she had a history of bone pain and autoimmune issues.
- - Tests revealed a tumor in her right ethmoid sinus, which was affecting her phosphate levels and causing her bone problems, linked to elevated levels of FGF23.
- - After phosphate replacement and surgery to remove the tumor, her health improved significantly, with normal levels of phosphate and FGF23, confirming the diagnosis of a phosphaturic mesenchymal tumor that caused osteomalacia.
Background: Chronic low-grade inflammation is observed across mental disorders and is associated with difficult-to-treat-symptoms of anhedonia and functional brain changes, reflecting a potential transdiagnostic dimension. Previous investigations have focused on distinct illness categories in people with enduring illness, but few have explored inflammatory changes. We sought to identify an inflammatory signal and the associated brain function underlying anhedonia among young people with recent-onset psychosis and recent-onset depression.
View Article and Find Full Text PDFCordyceps, an entomopathogenic fungus belonging to the Ascomycota phylum, is a familiar remedial mushroom that is extensively used in the traditional medicinal system, especially in South Asian nations. The significance of this genus' members in a range of therapeutic and biotechnological applications has long been acknowledged. The exceedingly valuable fungus Ophiocordyceps sinensis (Cordyceps sinensis) is found in the alpine meadows of Bhutan, Nepal, Tibet, and India, where it is severely harvested.
View Article and Find Full Text PDFArticle Synopsis
- Alternate proteins are becoming a popular, sustainable alternative to animal proteins, appealing especially to vegetarians and vegans, and can be sourced from legumes, grains, nuts, seeds, and advanced technologies are used to produce fungal and algal proteins.
- Despite their growing demand, there's a significant gap in consumer acceptance due to issues like lower bioavailability, reduced digestibility, and nutritional differences compared to traditional animal proteins.
- The review explores various sources and processing technologies for alternative proteins, discusses nutritional content and environmental sustainability, and emphasizes the need for overcoming challenges related to consumer acceptance, taste, and nutrient equivalency.
Trophoblast antigen 2 (Trop2) is a transmembrane glycoprotein upregulated in multiple solid tumours. Trop2-based passive immunotherapies are in clinical trials, while Trop2 targeting CAR-T cell-based therapies are also reported. Information about its T- and B-cell epitopes is needed for it to be pursued as an active immunotherapeutic target.
View Article and Find Full Text PDF