[Alterations in coronary arteries and frequency of episodes of transient myocardial ischemia in patients with ischemic heart disease with typical and atypical angina pectoris].

A total of 169 patients with ischemic heart disease were examined. Group I comprised 105 patients with angina pectoris, group II was 64 patients presenting with an untypical pain syndrome. A single affection of the coronary artery (CA) was more frequently seen in group II subjects (50 percent versus 16.

[Changes in left ventricular diastolic function and in tolerance to physical loading under the influence of finoptin in stenocardia patients].

A total of 45 patients aged 53.6 +/- 6.1 years who had Functional Class II-IV angina pectoris were examined.

[An evaluation of the role of paired loading tests in selecting the long-term drug therapy for patients with stable angina].

The examination of 208 patients with stable exercise-induced angina has demonstrated that the long-term (12 weeks and 12 months) antianginal effect can be predicted with a high accuracy from the results of acute pair exercise test using the drugs. The negative result of the test with verapamil is not informative due to the accumulation of its antianginal effect when the agent is used long. The long-term antianginal effect of nitrosorbide is determined not only by positive pair exercise test, but mainly by its dosage regimen during a day.

[Correlation of antianginal effect of corinfar and diastolic function in patients with ischemic heart disease].

The study was undertaken to examine 45 patients with coronary heart disease and 14 healthy subjects by using radionuclide ventriculography, apex- and echocardiographies, bicycle ergometry, transesophageal electrocardiostimulation before therapy and at the action peak of corinfar in a dose of 30 mg. It was shown that corinfar failed to affect the unaltered diastolic function of the left ventricle. The normalizing effect of corinfar on left ventricular stiffness was found to result in higher coronary reserve, significantly enhanced exercise tolerance and to be an important mechanism of antianginal effect of the drug.