Publications by authors named "A N Langnas"

Objective: Intestinal transplantation (ITx) has become an accepted option for children with serious complications from intestinal failure and parenteral nutrition (PN) dependence. We aimed to assess long-term growth and nutritional outcomes in these patients. We also assessed factors influencing nutritional status and ability to wean off tube feedings (TFs) after ITx.

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Background: Textbook outcome (TO) is a single composite score representing ideal care for a procedure or medical condition. Short bowel syndrome (SBS) patients are at high risk for complications and death. Our aim was to determine the incidence of and predictive factors for a TO in SBS patients.

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Importance: A new liver allocation policy was implemented by United Network for Organ Sharing (UNOS) in February 2020 with the stated intent of improving access to liver transplant (LT). There are growing concerns nationally regarding the implications this new system may have on LT costs, as well as access to a chance for LT, which have not been captured at a multicenter level.

Objective: To characterize LT volume and cost changes across the US and within specific center groups and demographics after the policy implementation.

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Article Synopsis
  • Normothermic regional perfusion (NRP) is a promising method for recovering livers from controlled donation after circulatory death (cDCD) donors, potentially enhancing transplant outcomes and expanding the donor pool in the US, where only 11.4% of deceased donor liver transplants are from cDCD donors.
  • This study compared liver transplant outcomes from cDCD donors recovered using NRP versus standard super rapid recovery (SRR) across 17 US transplant centers, focusing on outcomes like ischemic cholangiopathy and post-transplant complications.
  • Results showed that livers recovered via NRP had shorter hospital stays (7 days vs. 10 days) and none experienced primary
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Background: Normothermic regional perfusion (NRP) is a technique that is intended to enhance organ transplant outcomes from donation circulatory death (DCD) donors.

Study Design: A retrospective analysis of data from the Scientific Registry of Transplant Recipients was performed. DCD donors were screened for inclusion based on date of donation 2020 or later, and whether the heart was also recovered for transplantation.

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