10-µJ-level femtosecond pulse generation in the erbium CPA fiber source with microstructured hollow-core fiber assisted delivery and nonlinear frequency conversion.

We report on the development of a chirped pulse amplification (CPA) designed erbium fiber source with a hybrid high-power amplifier, which is composed of erbium-doped and erbium/ytterbium-co-doped double-clad large-mode-area fibers. Stretched pulses from the high-power amplifier with up to 21.9 µJ energy and 198.

Catastrophic damage in hollow core optical fibers under high power laser radiation.

The propagation of an optical discharge (OD) along hollow-core optical fibers (HCFs) is investigated experimentally. Silica-based revolver-type HCFs filled with atmospheric air were used as test samples. We observed that the average propagation velocity of an OD along the HCF (VAV) depends on the properties of the medium around the silica structure of the fiber.

Dose-Response Effect of Antibodies to S100 Protein and Cannabinoid Receptor Type 1 in Released-Active Form in the Light-Dark Test in Mice.

Earlier studies have shown that combination of antibodies to S100 protein and to cannabinoid receptor type 1 in released-active form (Brizantin) may possess anxiolytic properties and decrease nicotine dependence. Released-active form of antibodies is a novel approach that permits to modify natural functions of the target molecule (antigen) under investigation. The aim of the present study was to evaluate the anxiolytic-like effect of Brizantin in the light-dark test in mice, according to its ability to influence the number of entries into the lit compartment and the total time spent there.

Application of Negative Curvature Hollow-Core Fiber in an Optical Fiber Sensor Setup for Multiphoton Spectroscopy.

In this paper, an application of negative curvature hollow core fiber (NCHCF) in an all-fiber, multiphoton fluorescence sensor setup is presented. The dispersion parameter (D) of this fiber does not exceed the value of 5 ps/nm × km across the optical spectrum of (680-750) nm, making it well suited for the purpose of multiphoton excitation of biological fluorophores. Employing 1.

Large-surface-area diamond (111) crystal plates for applications in high-heat-load wavefront-preserving X-ray crystal optics.

Fabrication and results of high-resolution X-ray topography characterization of diamond single-crystal plates with large surface area (10 mm × 10 mm) and (111) crystal surface orientation for applications in high-heat-load X-ray crystal optics are reported. The plates were fabricated by laser-cutting of the (111) facets of diamond crystals grown using high-pressure high-temperature methods. The intrinsic crystal quality of a selected 3 mm × 7 mm crystal region of one of the studied samples was found to be suitable for applications in wavefront-preserving high-heat-load crystal optics.