[The comparative analysis of dorsopathy morbidity of adult population in the Russian Federation and separate Subjects of the Northern-West Federal Okrug in 2013-2022].

The dorsopathy is among of common causes of restriction of human life activity, affecting one's working capacity and quality of life. The purpouse of the study was to carry out comparative analysis of dorsopathy and spondylopathy morbidity of adult population in the Russian Federation and the Subjects of the Northern-West Federal Okrug in dynamics in 2013-2022. The statistical data of the Federal State Budget Institution "The Central Research Institute for Health Organization and Informatics of Minzdrav of Russia" was used.

Noninvasive Monitoring of Glycemia Level in Diabetic Patients by Wearable Advanced Biosensors.

We report on the possibility of noninvasive diabetes monitoring through continuous analysis of sweat. The prediction of the blood glucose level in diabetic patients is possible on the basis of their sweat glucose content due to the positive correlation discovered. The ratio between the blood glucose and sweat glucose concentrations for a certain diabetic subject is stable within weeks, excluding requirements for frequent blood probing.

[The application of information technologies in system of support of decision making in osteopathy].

The implementation of information technologies into treatment practice of modern health care significantly increases efficiency of diagnosis and treatment of dorsopathies. The purpose of the study is to develop software module to evaluate post-urological status of patients with spine dorsopathy to optimize diagnostic process and treatment planning. The article describes application of original software module to assess the post-urological status of patients with spine dorsopathy.

Fast Reaction of the Prussian Blue Based Nanozyme "Artificial Peroxidase" with the Substrates: Pre-Steady-State Kinetic Approach.

This letter introduces the pre-steady-state kinetic approach, which is traditional for evaluation of elementary constants in molecular (enzyme) catalysis, for nanozymes. Apparently, the most active peroxidase-mimicking nanozyme based on catalytically synthesized Prussian Blue nanoparticles has been chosen. The elementary constants () for the nanozymes' reduction by an electron-donor substrate (being the fastest stage according to steady-state kinetic data) have been determined by means of stopped-flow spectroscopy.

Polyazine nanoparticles as anchors of PQQ glucose dehydrogenase for its most efficient bioelectrocatalysis.

We report on the drop-cast production of glucose biosensors based on the most efficient bioelectrocatalysis by pyrroloquinoline quinone dependent glucose dehydrogenase (PQQ GDH). To orient the enzyme upon immobilization we suggest using poly(Methylene Green) (p(MG)) nanoparticles acting as anchors. Synthesis of polymeric anchors has been carried out in course of Methylene Green electropolymerization, which allowed to tune polymer-to-monomer ratio in the drop-cast mixtures varying the monomer concentration and applying different number of potential sweep cycles.