[Characterization of tuberculosis agent in different regions of Russia and its significance in assessment of the epidemiological situation].

The authors analyze M. tuberculosis viability in terms of growth speed and intensity, drug sensitivity; compare bacteriological data with epidemiological (morbidity, primary bacillarity in respiratory tuberculosis, bacillary focus in populations, population with fibrocavernous tuberculosis); range epidemiological and bacteriological indices; determine integral indices of epidemiological and bacteriological situation; calculate Spirman's rate. It is thought possible to use the above bacteriological indices in analysis of epidemiological situation concerning tuberculosis.

[Effect of antiseptics and redox-cycling agents on Corynebacterium ammoniagenes and related microorganisms in relation to synthesis of a new macroergic compound].

Sublethal concentration of the antiseptic composition Desoxon-1 was shown to provoke in cells of Corinebacterium ammoniagenes in a liquid medium the biosynthesis and accumulation of a novel macroergic 2-methylbutane-1,2,3,4-tetraol-2,4-cyclopyrophosphate. This substance is also synthesized when C. ammoniagenes is cultivated in a solid agar medium supplemented with benzylviologen.

[Effects of low-intensity garnet laser irradiation on microorganisms and wounds].

The influence of low-intensity garnet laser radiation a wavelength of 0.53 microns (green spectrum) on Mycobacterium tuberculosis (MT), nonspecific microflora and regeneration of aseptic and purulent wounds has been studied experimentally for the first time. Irradiation of MT and nonspecific microflora inoculations has shown that this type of laser radiation fails to stimulate growth of MT and nonspecific microflora and has an inhibiting action on MT manifested by delayed MT growth, a lower number of dimensions of the growth colonies as compared to those of the control inoculations and has a bacteriostatic action on micrococci and Neisseria organisms.

[The action of helium-neon laser radiation on the growth of Mycobacterium tuberculosis].

The growth properties of M. tuberculosis subjected to the action of helium-neon laser radiation was studied. Laser radiation was shown to change the quantitative and qualitative composition of mycobacterial population.

[The effect of an ozone-oxygen mixture on Mycobacterium tuberculosis and conditionally pathogenic microorganisms].

The impact of a gaseous ozone-oxygen mixture (OOM) on Mycobacterium tuberculosis (MBT) and opportunistic microorganisms was studied. It was demonstrated that on 15- and 30-min exposure, OOM caused a significant decrease in the number of colonies of the grown microorganisms as compared with the control. The OOM mixture produced the highest effect of the MBT suspension, which is likely to be related to a greater surface of ozone contact with a cell than with a dense medium, and higher concentration of ozone and its highly active radicals that arise from a treatment process.