Publications by authors named "A N Gachanja"

Pharmaceuticals and personal care products (PPCPs) are an indispensable component of a healthy society. However, they are well-established environmental contaminants, and many can elicit biological disruption in exposed organisms. It is now a decade since the landmark review covering the top 20 questions on PPCPs in the environment (Boxall et al.

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Herein, we report a stimuli-responsive hydrogel with inhibitory activity against prepared by chemical crosslinking of carboxymethyl chitosan (CMCs) and hydroxyethyl cellulose (HEC). The hydrogels were prepared by esterification of chitosan (Cs) with monochloroacetic acid to produce CMCs which were then chemically crosslinked to HEC using citric acid as the crosslinking agent. To impart a stimuli responsiveness property to the hydrogels, polydiacetylene-zinc oxide (PDA-ZnO) nanosheets were synthesized in situ during the crosslinking reaction followed by photopolymerization of the resultant composite.

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Article Synopsis
  • The study examined the levels and distribution of pharmaceutical residues in peri-urban creeks along the Kenya coast, specifically Mombasa and Gazi Bay, focusing on compounds like acetaminophen, antibiotics, and antiepileptics.
  • The highest concentrations of residues were found in Tudor Creek, with acetaminophen and nevirapine being the most frequently detected compounds.
  • Ecological risk assessments indicated that some pharmaceuticals posed low to medium risk, while nevirapine presented a medium to high ecological risk to local marine ecosystems, highlighting the need for further research on these substances in marine environments.
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Over reliance on charcoal has accelerated deforestation in sub-Saharan Africa. Seeking alternative sustainable and environmentally friendly sources of biomass energy to meet the escalating energy demand is therefore vital. However, limited evidence exists on the concentrations of toxic emissions of different biomass fuels.

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Background: Vector control is an essential component in prevention and control of malaria in malaria endemic areas. Insecticide treated nets is one of the standard tools recommended for malaria vector control. The objective of the study was to determine physical integrity and insecticidal potency of long-lasting insecticidal nets (LLINs) used in control of malaria vector in Kirinyaga County, Kenya.

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