Publications by authors named "A Munshea"

Introduction: Measles is an extremely contagious viral disease that can be prevented through vaccination. It is caused by the measles virus and presents with symptoms such as high fever, cough, runny nose, conjunctivitis, and a distinctive rash. Complications may include pneumonia, diarrhoea, and neurological issues.

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The genetic analysis of the Dengue virus circulating in Ethiopia's Afar region, in 2023, identified three distinct introductions with spatiotemporal clustering linked to genomes from Asia and Italy. These findings are crucial for enhancing prevention and control strategies, reinforcing the necessity to provide sustainable tools for genomic epidemiology in Africa.

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Article Synopsis
  • This study focused on the relationship between helminth infections and the effectiveness of the QuantiFERON-TB Gold Plus (QFT-Plus) test for detecting latent TB in a TB-endemic area of Ethiopia.* -
  • Among 314 participants, 16.9% were found to be infected with helminths, but overall QFT-Plus positivity was similar for both helminth-positive and -negative groups, although higher hookworm burdens corresponded with lower test positivity.* -
  • The results indicate that the type and intensity of helminth infections may impact immune response, suggesting the need for more extensive research to fully understand these dynamics.*
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  • Cutaneous leishmaniasis (CL) in Ethiopia, caused by the Leishmania aethiopica parasite, shows multiple clinical forms that are not linked to genetic differences in the parasite's genome or variations in immune system responses among patients.
  • A study analyzed genetic data from 48 parasite isolates and immune signatures from 129 CL patients, finding no significant associations between the genetic variants or immune markers and the different clinical presentations of CL.
  • The research concluded that while there were some differences in chemokines when comparing CL patients to healthy controls, the overall immune response did not significantly vary between the clinical forms of CL.
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