Publications by authors named "A Munoz-Barrutia"
This manuscript showcases the latest advancements in deepImageJ, a pivotal Fiji/ImageJ plugin for bioimage analysis in life sciences. The plugin, known for its user-friendly interface, facilitates the application of diverse pre-trained convolutional neural networks to custom data. The manuscript demonstrates several deepImageJ capabilities, particularly in deploying complex pipelines, three-dimensional (3D) image analysis, and processing large images.
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- Bioimage analysis (BIA) enhances biological research by providing objective, quantitative methods for microscopy, overcoming biases linked to subjective analysis.
- Establishing dedicated BIA support in academic institutions is essential for improving research quality and facilitating scientific advancements.
- The document outlines challenges facing BIA, such as lack of training and recognition, and proposes strategies for improvement, including better training resources, standardization of tools, and increased collaboration and funding.
Alzheimer's Disease Detection in EEG Sleep Signals.
IEEE J Biomed Health Inform
October 2024
Article Synopsis
- There is a strong link between Alzheimer's disease (AD), sleep disorders, and the onset of Mild Cognitive Impairment (MCI), with sleep pattern disruptions often occurring before cognitive decline.
- This study explores the use of sleep-related EEG signals from polysomnography (PSG) to detect AD early, focusing on semi-supervised Deep Learning models due to the challenge of having limited labeled data.
- Results indicate that a specific semi-supervised model outperformed unsupervised approaches and achieved high accuracy (90-94%) in classifying EEG signals, emphasizing the importance of spatio-temporal feature extraction in early AD detection.
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most prevalent kidney genetic disorder, producing structural abnormalities and impaired function. This research investigates its evolution on mouse models, utilizing a combination of histology imaging, Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) to evaluate its progression thoroughly. ADPKD has been induced in mice via PKD2 gene knockout, followed by image acquisition at different stages.
View Article and Find Full Text PDFThe enteric nervous system (ENS) consists of an extensive network of neurons and glial cells embedded within the wall of the gastrointestinal (GI) tract. Alterations in neuronal distribution and function are strongly associated with GI dysfunction. Current methods for assessing neuronal distribution suffer from undersampling, partly due to challenges associated with imaging and analyzing large tissue areas, and operator bias due to manual analysis.
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