The application of immunocytochemistry (ICC), as a diagnostic and predictive tool in the workup of head and neck lesions has followed the changes and progresses in the surgical pathology evaluation. The contribution of ICC has shown a significant role in the head and neck cytology, demonstrating as its contribution can support the diagnosis in many lesions. Furthermore, its role has been evolving as an important asjuvant tool in targeted therapies.
View Article and Find Full Text PDFBackground: Ibuprofen is a main cause of drug hypersensitivity reactions in children. The gold standard for diagnosis is the drug provocation test (DPT).
Objective: We aimed to create a clinical risk-stratification tool to guide this high-risk procedure.
Endometrial carcinoma is a heterogeneous group of malignancies characterized by distinct histopathological features and genetic underpinnings. The 2020 WHO classification has provided a comprehensive framework for the categorization of endometrial carcinoma. However, it has not fully addressed the spectrum of uncommon entities that are currently not recognized by the 2020 WHO and have only been described in the form of small case series and case reports.
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