Publications by authors named "A Mouly"
Article Synopsis
- Parkinson's disease (PD) is not only characterized by motor coordination issues but also by sensory and cognitive impairments, including altered respiration patterns, which are influenced by different behavioral states.
- A study using a neurotoxin-induced rat model of PD found that these rats exhibited higher respiratory frequencies and amplitudes during quiet waking and exploration compared to control rats, with no notable differences during sleep.
- The research highlights the need to consider how behavioral states affect respiration in PD, while also indicating that olfactory abilities, measured through sniffing responses, did not significantly differ between PD rats and controls.
The Human Affectome.
Daniela Schiller Alessandra N C Yu Nelly Alia-Klein Susanne Becker Howard C Cromwell Anne-Marie Mouly
Neurosci Biobehav Rev
March 2024
Article Synopsis
- Theoretical perspectives in the affective sciences have increased in variety rather than converging due to differing beliefs about the nature and function of human emotions.
- A teleological principle is proposed to create a unified approach by viewing human affective phenomena as algorithms that adapt to comfort or monitor these adaptations.
- This framework aims to organize existing theories and inspire new research in the field, leading to a more integrated understanding of human affectivity through the concept of the Human Affectome.
In humans, screams have strong amplitude modulations (AM) at 30 to 150 Hz. These AM correspond to the acoustic correlate of perceptual roughness. In bats, distress calls can carry AMs, which elicit heart rate increases in playback experiments.
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- The study investigates how rats of different ages (infants, juveniles, adults) respond to odors by measuring their sniffing behavior and respiratory rates.
- It finds that adults have a higher peak sniffing rate than younger rats, and younger rats show a faster decline in their sniffing response when exposed to the same odor repeatedly.
- Additionally, when the odor is associated with a foot-shock, adults and infants maintain a heightened respiratory rate, while juveniles do not, indicating variations in olfactory processing and learning across developmental stages.
Memory consolidation involves reorganization at both the synaptic and system levels. The latter involves gradual reorganization of the brain regions that support memory and has been mostly highlighted using hippocampal-dependent tasks. The standard memory consolidation model posits that the hippocampus becomes gradually less important over time in favor of neocortical regions.
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