Polyoxometalate exerts broad-spectrum activity against human respiratory viruses hampering viral entry.

Human respiratory viruses have an enormous impact on national health systems, societies, and economy due to the rapid airborne transmission and epidemic spread of such pathogens, while effective specific antiviral drugs to counteract infections are still lacking. Here, we identified two Keggin-type polyoxometalates (POMs), [TiWCoO] (TiWCo) and [TiPWO] (TiPW), endowed with broad-spectrum activity against enveloped and non-enveloped human respiratory viruses, i.e.

Discovery of Polythioplatinate(II) [PtS(SO)] and Study of Its Solution and Catalytic Properties.

We have discovered the first polythioplatinate(II), [PtS(SO)] (), which was synthesized in aqueous basic medium (pH 11) by hydrothermal heating at 150 °C. Polyanion comprises a discrete, triangular assembly of three Pt ions linked by two μ-sulfido ligands, and their square-planar coordination geometry is completed by two terminal S-bound sulfito ligands. Polyanion was isolated as a hydrated sodium salt, Na[Pt(μ-S)(SO)]·22HO (), which was characterized in the solid state by single-crystal X-ray diffraction, Fourier-transform infrared spectroscopy, thermogravimetric analysis, X-ray photoelectron spectra, and elemental analysis, in solution by Pt NMR and atomic absorption spectroscopy, and in the gas phase by electrospray ionization mass spectrometry.

Organorhodium(III)- and Iridium(III)-Substituted 20-Tungstobismuthates(III) and -Antimonates(III), [(MCp*)XWO] (M = Rh and Ir; X = Bi and Sb).

The synthesis of four organometallic RhCp*- and IrCp*-containing heteropoly-20-tungstates, [{RhCp*}BiWO] (), [{IrCp*}BiWO] (), [{RhCp*}SbWO] (), and [{IrCp*}SbWO] () has been accomplished by reaction of (MCp*Cl) with [XWO(OH)] in aqueous solution at pH 6 and 70 °C. The four polyanions - were structurally characterized in the solid state by single-crystal XRD, FTIR, and TGA and in solution by W and C NMR. For the Rh derivatives and the W-Rh coupling ( 3.

Discovery of a Neutral 40-Pd-Oxo Molecular Disk, [PdO(OH){(CH)AsO}]: Synthesis, Structural Characterization, and Catalytic Studies.

We report on the synthesis and structural characterization of a giant, discrete, and neutral molecular disk, [PdO(OH){(CH)AsO}] (), comprising a 40-palladium-oxo core that is capped by 16 dimethylarsinate moieties, resulting in a palladium-oxo cluster (POC) with a diameter of ∼2 nm. , which is the largest known neutral Pd-based oxo cluster, can be isolated either as a discrete species or constituting a 3D H-bonded organic-inorganic framework (HOIF) with a 12-tungstate Keggin ion, [SiWO] or [GeWO]. H and C NMR as well as H-DOSY NMR studies indicate that is stable in aqueous solution, which is also confirmed by ESI-MS studies.

Palladium(II)-Containing Tungstoarsenate(V), [Pd(AsWO)], and Its Catalytic Properties.

We have synthesized and structurally characterized the 4-palladium(II)-containing 30-tungsto-4-arsenate(V), [Pd(AsWO)] (), which represents the first palladium(II)-containing tungstoarsenate(V). The title polyanion was prepared by a simple one-pot procedure in aqueous medium and characterized by single-crystal X-ray diffraction (XRD), thermogravimetric analysis (TGA), cyclic voltammetry, elemental analysis, and W nuclear magnetic resonance (NMR), infrared (IR), and ultraviolet-visible (UV-vis) spectroscopies. Polyanion consists of four Pd ions that are coordinated in a square-planar geometry to two trilacunary [AsWO] Wells-Dawson fragments resulting in a sandwich-type assembly.