Publications by authors named "A Mosbah"
Purpose: To create a computer-aided prediction (CAP) system to predict Wilms tumor (WT) responsiveness to preoperative chemotherapy (PC) using pre-therapy contrast-enhanced computed tomography (CECT).
Materials And Methods: A single-center database was reviewed for children <18 years diagnosed with WT and received PC between 2001 and 2021. Patients were excluded if pre- and post-PC CECT were not retrievable.
Background: Endoplasmic reticulum stress with protein misfolding has been introduced as a key pathogenetic mechanism in lupus nephritis (LN). Pregnancy is thought to exaggerate proteostasis, which leads to the accumulation of potentially pathogenic misfolded proteins in the urine, serum, and placenta particularly in women with preeclampsia. The detection of misfolded proteins is made using Congo red stain, which is referred to as congophilia.
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- The Sterile Insect Technique (SIT) uses sterilized male pests to control populations without harming the environment, by mating them with wild females who then don't produce offspring.
- Recent studies show that adding probiotics to the diet of medflies (Ceratitis capitata) significantly improves their quality, which could enhance SIT's effectiveness.
- An analysis of medflies showed that probiotic supplementation altered their metabolomic profile, leading to the identification of key metabolites that could play roles in pest control strategies.*
The escalating challenge of antibiotic resistance significantly threatens global health, underscoring the critical need for new antimicrobial agents. Venoms, increasingly recognized as reservoirs of bioactive compounds with diverse pharmacological effects, have been the focus of recent research. This work evaluates the use of various screening methodologies in assessing the antimicrobial activities of 185 venoms against some gram positive and gram negative bacteria, including E.
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- - The study investigates how heavy metals and trace elements (HMTE) contribute to bladder cancer (BC), focusing on mechanisms such as mitochondrial dysfunction, oxidative stress, and specific protein kinases.
- - Researchers analyzed samples from 125 BC patients and 72 controls, measuring various heavy metals and assessing genetic markers related to mitochondrial function and oxidative stress using advanced laboratory techniques.
- - Results revealed that elevated levels of several heavy metals in BC tissues correlated with increased expression of certain genes and markers associated with mitochondrial dysfunction and oxidative stress, highlighting the need to reduce exposure to these toxic elements to potentially lower BC risk.