O-glycosylation of secreted and membrane-bound proteins is an important post-translational modification that affects recognition of cell surface receptors, protein folding, and stability. However, despite the importance of O-linked glycans, their biological functions have not yet been fully elucidated and the synthetic pathway of O-glycosylation has not been investigated in detail, especially in the silkworm. In this study, we aimed to investigate O-glycosylation in silkworms by analyzing the overall structural profiles of mucin-type O-glycans using LC-MS.
View Article and Find Full Text PDFA complete thoracoscopic right lower lobectomy was successfully performed for a 74-year-old woman with an anomalous right middle lobe pulmonary vein, forming a common trunk of V4+5 and V6 . Preoperative three-dimensional computed tomography was useful to identify the vascular anomaly and contributed to perform safe surgery under the thoracoscopy.
View Article and Find Full Text PDFWe report a case of superior mesenteric artery( SMA) embolism on the seventh day after lung resection. The patient is a 76-year-old woman. She underwent complete thoracoscopic left upper lobectomy and systematic lymph node dissection for adenocarcinoma of the lung.
View Article and Find Full Text PDFPurpose: Postoperative nausea and vomiting (PONV) is a common adverse event after surgery. Remimazolam is a novel sedative agent recently approved for general anesthesia in Japan. This study evaluated the efficacy of remimazolam in the incidence of PONV after laparoscopic gynecological surgery under general anesthesia.
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