Publications by authors named "A Montalvo"
Unlabelled: CYP2C9 metabolizes approximately 20% of clinically administered drugs. Several single-nucleotide polymorphisms (SNPs) of CYP2C9 (e.g.
View Article and Find Full Text PDFBackground: While allografts are commonly used for anterior cruciate ligament reconstruction (ACLR), evidence to guide specific allograft selection is lacking.
Purpose: To compare clinical and graft failure rates after ACLR using soft tissue-only allografts and bone-soft tissue allografts in adults.
Study Design: Systematic review and meta-analysis; Level of evidence, 4.
Article Synopsis
- Young athletes (≤18 years) face a high risk of ACL graft failure, with current studies indicating significant variation in failure rates among different autograft types used for reconstruction.
- A systematic review analyzed 24 studies and found that hamstring tendon (HT) autografts had the highest failure rate at 11.8%, while bone-patellar tendon-bone (BPTB) and quadriceps tendon (QT) had lower failure rates at 7.9% and 2.7%, respectively.
- The findings suggest that while HT is commonly used, BPTB and QT may be more effective options for reducing reinjury risk in young athletes undergoing ACL reconstruction.
Background: The concept of amnestic mild cognitive impairment (aMCI) was developed to identify patients at an initial stage of Alzheimer's disease (AD). However, some patients with aMCI do not present biomarkers of amyloid pathology or neuronal injury.
Objective: To know the natural history of amyloid-negative and neurodegeneration-negative patients with aMCI, namely to ascertain: 1) whether these patients remain cognitively stable or they present a slow decline in neuropsychological tests; 2) whether the memory complaints subside with the apparently benign clinical course of the disorder or if they persist along the time.
Article Synopsis
- - The study investigates the use of all-soft tissue quadriceps tendon (ASTQT) autografts for ACL reconstruction in young athletes, focusing on return-to-sport (RTS) rates and reinjury rates.
- - A total of 656 patients aged 14-22 underwent primary ACLR, with 395 responding to a follow-up survey, revealing high RTS rates of 87.7% for males and 82.8% for females, and low revision rates.
- - The findings suggest that ASTQT autografts lead to favorable outcomes in ACLR, with similar rates of subsequent ACL injuries for both genders, emphasizing the graft's utility in young athletes.