Publications by authors named "A Montalto"
: Pulmonary arterial elastance (Ea) is a helpful parameter to predict the risk of acute postoperative right ventricular failure (RVF) after left ventricular assist device (LVAD) implantation. A new method for calculating Ea, obtained by the ratio between transpulmonary gradient and stroke volume (Ea), has been proposed as a more accurate measure than the Ea obtained as the ratio between pulmonary artery systolic pressure and stroke volume (Ea). However, the role of Ea in predicting acute RVF post-LVAD implantation remains unclear.
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- Lichen sclerosus (LS) is a long-lasting skin condition that is often treated with potent topical steroids, which can have side effects.
- A previous study showed that OZOILE (stable ozonides) can effectively treat LS in children by reducing inflammation and promoting tissue healing, similar to steroids.
- This research evaluated inflammatory processes in foreskins affected by LS, finding that OZOILE increases beneficial NRF2 and SOD2 levels without triggering harmful pathways, while steroids reduce some inflammatory markers but don't affect NRF2 or SOD2 levels.
Article Synopsis
- The study compares the use of Impella pumps and VA-ECMO in treating patients with cardiogenic shock, focusing on clinical outcomes, resource use, and quality of life.
- Conducted across 17 clinical centers in Italy, the research involves both prospective data collection for Impella patients and retrospective data matching for VA-ECMO patients to assess cost-effectiveness and budget impact.
- As of May 2024, most centers have received ethical approval for the study, with plans to publish results in peer-reviewed journals for wider dissemination.
Article Synopsis
- * Differences in how drugs are metabolized by sex highlight the need for sex-specific medical approaches, yet awareness of this issue is still limited.
- * The paper focuses on evaluating therapeutic strategies for managing common diseases affecting women, emphasizing the importance of individualized treatment guidelines based on gender.
Article Synopsis
- - Gender significantly influences cardiovascular risk factors and affects prevention, clinical pathways, diagnosis, and treatment, highlighting the need for a more inclusive approach in healthcare.
- - Despite its importance, sex and gender differences in cardiovascular care are often overlooked, leading to disparities in patient outcomes and access to quality care.
- - The paper emphasizes the necessity of increasing female representation in clinical trials and leadership roles, advocating for tailored treatment strategies that consider gender influences on cardiovascular diseases.