Publications by authors named "A Monsegue"

Background: Exercise and nutrition interventions can slow ageing-induced decline in physiology. However, effects are heterogeneous and usually studied separately per outcome domain. In the VOILA study, we simultaneously study various health outcomes relevant for older adults and the inter-individual heterogeneity in response to a lifestyle intervention.

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Article Synopsis
  • COPD leads to muscle dysfunction, which may be linked to the spatial relationship between satellite cells and capillaries in muscle tissue.
  • A study compared muscle biopsies from 18 COPD patients and 18 healthy older adults, assessing muscle fiber types, satellite cell numbers, and capillary proximity.
  • Results showed COPD patients had more type II muscle fibers, reduced capillarisation, and greater distances between satellite cells and capillaries, potentially impacting satellite cell function in COPD.
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Knee osteoarthritis is associated with deficits in muscle strength, muscle mass, and physical functioning. These muscle-related deficits are acutely exacerbated following total knee arthroplasty (TKA) and persist long after surgery, despite the application of standardized rehabilitation programs that include physical/functional training. Resistance exercise training (RET) has been shown to be a highly effective strategy to improve muscle-related outcomes in healthy as well as clinical populations.

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Background & Aim: In hospitalized patients, daily protein intake remains far below WHO requirements for healthy adults (0.8 g·kg·d) as well as ESPEN guidelines for patients (1.2-1.

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