Publications by authors named "A Mokrani"
The extraction of polyphenols from myrtle (Myrtus communis L.) fruits using a conventional solid-liquid extraction was optimized using a single-factor experiment approach. The influence of several parameters such as type of solvent (50% acetone, 50% methanol, 50% ethanol, and water), solvent concentration (30-100%; v/v), solvent acidity (0-0,1 N), temperature (20°C-40°C) and time (30-360 min) on the yield extraction of total phenolic content (TPC), total flavonoid content (TFC), total proanthocyanidin content (TPAC), and on the antioxidant activity: DPPH-radical scavenging activity (DPPH-RSA), ABTS-radical scavenging activity (ABTS-RSA) and ferric reducing power (FRP) was studied.
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- Snakebite envenoming (SBE) is a major public health problem in tropical areas, especially Africa, where it causes a high number of fatalities and serious health issues due to ineffective antivenom treatments.
- This study focuses on developing nanobodies as a new type of treatment against cobra venoms, investigating toxic venom fractions and their interaction with acetylcholine receptors.
- The research identified two particularly deadly venom fractions, F5 and F6, and demonstrated that combining specific nanobodies could neutralize these venoms effectively in mice, revealing the complex nature of cobra venom's lethal effects.
Aim: To describe the management and treatment practices of venous thromboembolism (VTE) in cancer patients, assess compliance with the 2023 European Society for Medical Oncology recommendations, and identify factors that may limit or influence their application.
Methods: We conducted, in a Tunisian center, a retrospective study that included patients treated for cancer or hematologic malignancies and diagnosed with deep vein thrombosis (DVT) and/or pulmonary embolism between January 1, 2022, and August 1, 2023.
Results: The study involved 90 patients.
DNA methylation, an essential epigenetic alteration, is tightly linked to a variety of biological processes, such as immune response. To identify the epigenetic regulatory mechanism in Pacific oyster (Crassostrea gigas), whole-genome bisulfite sequencing (WGBS) was conducted on C. gigas at 0 h, 6 h, and 48 h after infection with Vibrio alginolyticus.
View Article and Find Full Text PDFIntroduction: Oncologists are often confronted with patients at the end of their lives who are suffering. This can lead to anxiety and depressive disorders (ADD), affecting the quality of the doctors's quality of life.
Aim: To compare the level of ADD among doctors practicing at Salah Azaiez Institute (SAI) in Tunis with doctors who do not treat cancer patients, while identifying any factors associated with these disorders.