Publications by authors named "A Mitridate de Novara"

Article Synopsis
  • The study analyzed 20 years of data on severe asthma exacerbation (SAE) admissions in adult patients at 40 ICUs in the greater Paris area to understand trends in patient characteristics, management, and outcomes.
  • Admissions for SAE significantly declined over the two decades, dropping from 2.84% of total ICU admissions in 1997-2001 to 1.05% in both 2007-2011 and 2012-2016.
  • Although the use of mechanical ventilation remained low, factors like older age and severe symptoms were linked to higher ICU mortality rates, while overall ICU and hospital mortality decreased over the study period.
View Article and Find Full Text PDF

It is now well known that patients with severe COVID-19 are at risk for developing invasive pulmonary aspergillosis (IPA). Nevertheless, the symptomatology of IPA is often atypical in mechanically ventilated patients and the radiological aspects of SARS CoV-2 pneumonia and IPA are difficult to differentiate. In this context, the significance of the presence of Aspergillus in respiratory tract samples (detected by culture, galactomannan antigen, or specific PCR) is not yet fully understood.

View Article and Find Full Text PDF

Background: In-hospital cardiac arrest(IHCA) has received little attention compared with out-of-hospital cardiac arrest.

Aim: To address the paucity of data on IHCA patients, we examined key features, variations in mortality and predictors of death among patients admitted in French intensive care units(ICUs) from 1997 to 2015.

Methods: Using the database of the Collège des Utilisateurs de Bases de données en Réanimation(CUB-Réa) that prospectively collects data from ICUs in the greater Paris area, we determined temporal trends in the incidence of IHCA, patients' outcomes, crude and Simplified Acute Physiology Score(SAPS)-II Standardized mortality and predictors of in-ICU mortality.

View Article and Find Full Text PDF

Background: Patients with severe COVID-19 have emerged as a population at high risk of invasive fungal infections (IFIs). However, to our knowledge, the prevalence of IFIs has not yet been assessed in large populations of mechanically ventilated patients. We aimed to identify the prevalence, risk factors, and mortality associated with IFIs in mechanically ventilated patients with COVID-19 under intensive care.

View Article and Find Full Text PDF