Publications by authors named "A Minguez-Castellanos"
Neuropsychological assessment protocol in an ongoing randomized controlled trial on posterior subthalamic area vs. ventral intermediate nucleus deep brain stimulation for essential tremor.
Front Neurol
October 2023
Objective: Patients with essential tremor (ET) may experience cognitive-affective impairment. Deep brain stimulation (DBS) of different targets, such as the ventral intermediate nucleus (VIM) of the thalamus or the posterior subthalamic area (PSA), has been shown to be beneficial for refractory ET. However, there is little evidence regarding the possible neuropsychological effects of PSA-DBS on patients with ET, and there are few studies comparing it with VIM-DBS in this population.
View Article and Find Full Text PDFIntroduction: Acute ischemic stroke therapy has improved in recent decades, decreasing the rates of disability and death among stroke patients. Unfortunately, all health care systems have geographical disparities in infrastructure for stroke patients. A centralized telestroke network might be a low-cost strategy to reduce differences in terms of geographical barriers, equitable access, and quality monitoring across different hospitals.
View Article and Find Full Text PDFArticle Synopsis
- Neurologic impairment can last for months after severe COVID-19 infection due to ongoing inflammation.
- A study analyzed cognitive functions in 152 patients recovering from severe SARS-CoV-2 infection, finding significant issues with memory, executive functions, and attention, alongside elevated anxiety and depression rates.
- The study also identified increased levels of certain plasma biomarkers in these patients, raising concerns about potential long-term cognitive effects or the risk of neurodegenerative diseases.
Objective: We aimed to investigate the prevalence of TOR1A, GNAL and THAP1 variants as the cause of dystonia in a cohort of Spanish patients with isolated dystonia and in the literature.
Methods: A population of 2028 subjects (including 1053 patients with different subtypes of isolated dystonia and 975 healthy controls) from southern and central Spain was included. The genes TOR1A, THAP1 and GNAL were screened using a combination of high-resolution melting analysis and direct DNA resequencing.