Publications by authors named "A Milesi"

Article Synopsis
  • The study investigates how spatial disorientation and behavioral issues in spatial cognition manifest in prodromal Alzheimer's disease (AD) compared to normal aging and mild cognitive impairment (MCI).
  • A sample of 58 elderly participants, including those with mild cognitive impairment, subjective cognitive decline, and healthy controls, was tested using the Detour Navigation Test and smartphone GPS tracking to assess wrong turns and gait patterns.
  • Results indicated that MCI patients made more wrong turns than the other groups, and the presence of the ApoE-ε4 genotype was linked to poorer spatial processing and slower gait in real-world navigation tasks.
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Introduction: In recent years, the concept of epistemic trust has emerged as a critical factor in understanding psychopathology, particularly within the context of personality disorders. A self-report instrument, the Epistemic Trust, Mistrust, and Credulity Questionnaire (ETMCQ), has demonstrated its validity among English and Italian adult populations. However, extending its applicability to adolescents is essential for comprehending the role of epistemic trust in the development of mental disorders.

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Two-dimensional in vitro cultures have represented a milestone in biomedical and pharmacological research. However, they cannot replicate the architecture and interactions of in vivo tissues. Moreover, ethical issues regarding the use of animals have triggered strategies alternative to animal models.

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Mentalization is the ability to interpret actions as caused by intentional mental states. Moreover, mentalization facilitates the development of epistemic trust (ET), namely, the ability to evaluate social information as accurate, reliable, and relevant. Recent theoretical literature identifies mentalization as a protective factor, contrasting psychopathology and emotional dysregulation.

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Standardized personality tests compare the test taker's scores to those of a large sample of individuals representing normative expectations. However, what is psychologically in one historical context may not be similarly normal in another, so the recent spread of a new coronavirus, SARS-Cov-2 (COVID-19), may have implications for what should normally be expected of a nonclinical person taking a personality test shortly after this dramatic event. To address this research question, we administered the Personality Assessment Inventory (PAI) and the Rorschach Performance Assessment System (R-PAS) to 60 nonclinical volunteers from Italy and compared their scores with the official normative reference values of the two tests, which had been established before COVID-19.

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