Publications by authors named "A Milazzo"

This work focuses on the coupling of trimmed shell patches using Isogeometric Analysis, based on higher continuity splines that seamlessly meet the requirement of Kirchhoff-Love-based discretizations. Weak enforcement of coupling conditions is achieved through the symmetric interior penalty method, where the fluxes are computed using their correct variationally consistent expression that was only recently proposed and is unprecedentedly adopted herein in the context of coupling conditions. The constitutive relationship accounts for generically laminated materials, although the proposed tests are conducted under the assumption of uniform thickness and lamination sequence.

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  • The study focuses on identifying markers that can predict adverse events in patients who had acute myocarditis (AM) to optimize follow-up care.
  • Researchers analyzed data from 248 AM patients, revealing that complicated clinical presentation (CCP) is a strong predictor of major cardiac events compared to other factors like septal late gadolinium enhancement and left ventricular ejection fraction.
  • Findings indicate that while major events post-AM are rare, using CCP, LGE, and LVEF<50% together is effective for identifying those at risk, aiding clinicians in patient monitoring.
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Haemodynamic forces (HDFs), which represent the forces exchanged between blood and surrounding tissues, are critical in regulating the structure and function of the left ventricle (LV). These forces can be assessed on cardiac magnetic resonance or transthoracic echocardiography exams using specialized software, offering a non-invasive alternative for measuring intraventricular pressure gradients. The analysis of HDFs can be a valuable tool in improving our understanding of cardiovascular disease and providing insights beyond traditional diagnostic and therapeutic approaches.

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  • Infectious diseases like Invasive Meningococcal Disease (IMD) pose ongoing public health challenges due to their severe impact and the fact that they're not fully vaccine-preventable.
  • A systematic review of 39 studies on IMD outbreaks revealed that most public health responses were reactive rather than proactive, often affecting entire communities instead of focusing on high-risk groups.
  • The findings highlighted a critical need for better reporting standards and comprehensive data to improve public health responses for IMD and future infectious disease outbreaks.
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  • * Atrial fibrillation (AF) is a significant concern for HCM patients, indicating disease progression and increasing risks related to heart failure, blood clots, and overall quality of life.
  • * The review focuses on understanding how AF develops in HCM, particularly through changes in the left atrium, and discusses the unique challenges in managing AF for these patients.
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