Publications by authors named "A Mihaescu"

Hepatitis C virus (HCV) infection is a major global public health concern, particularly in hemodialysis (HD) patients. This study aims to evaluate the demographic, clinical, and laboratory characteristics of HCV-positive patients undergoing HD and assess the long-term impact of direct-acting antivirals (DAAs) on patient outcomes. Moreover, a narrative review aims to summarize the current knowledge regarding HCV treatment in HD patients.

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The increase in bacterial resistance is currently a global burden for the health care system. In order to evaluate the resistance rates of several bacteria from the most encountered cultures in clinical practice, we performed a retrospective analysis of all of the positive cultures from the year 2021 in a tertiary care hospital in Romania. Our analysis captured 3299 positive cultures.

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Article Synopsis
  • Acute kidney disease (AKD) is a significant risk factor for increased mortality and progression to chronic kidney disease (CKD) in both adults and children, though data on children is limited.
  • A study of 736 children aged 2-18 with acute kidney injury (AKI) revealed a 17% incidence of AKD, with older age and specific biological parameters linked to its development, though certain factors like anaemia were identified as increasing risks independently.
  • The study concluded that AKD, along with specific AKI causes like glomerulonephritis and acute tubular necrosis, notably raised the risk of mortality and new-onset CKD in affected children.
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Chronic kidney disease patients treated by hemodialysis present a high cardiovascular morbidity and mortality. There is an imperative need for novel biomarkers for identifying these patients and to offer possible therapeutically interventions. We performed a prospective observational cohort study on 77 patients in the period of October 2021-October 2023.

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(1) Background: The relationship between chronic kidney disease (CKD) and urological cancers is complex, as most of these cancers are diagnosed in patients with advanced ages, when the kidney function may be already impaired. On the other hand, urological cancers could represent a risk factor for CKD, significantly reducing the life expectancy of the patients. The main objective of our study was to analyze the impact of CKD on the overall mortality of patients diagnosed with the most frequent types of urological cancers.

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