Publications by authors named "A Michele Schuler"

Enhanced biological phosphorus removal (EBPR) water resource recovery facilities (WRRFs) often fail to meet phosphorus discharge permit limits, indicating a need to improve EBPR to reduce environmental phosphorus discharges. EBPR designs are largely based on the Accumulibacter polyphosphate accumulating organism (PAO) metabolism, while understudied Tetrasphaera PAOs are equally important to EBPR in many facilities worldwide. Anaerobic organic carbon competition is believed to be a key driver of EBPR reliability.

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The simultaneous combination of TMS with fMRI has emerged as a promising means to investigate the direct interaction between stimulation-induced changes at the behavioral and neural activity level. This enables the investigation of whole brain neurobehavioral interactions underlying cognitive disruption or facilitation. Yet to date, the literature on interleaved TMS-fMRI in cognitive neuroscience is sparse and neuromodulatory patterns of different TMS protocols are still poorly understood.

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Article Synopsis
  • OGG1 (8-oxoguanine DNA glycosylase-1) is essential for DNA repair, particularly in removing damaged DNA caused by oxidation, and its deficiency in mice leads to increased obesity and metabolic issues from a high-fat diet (HFD).
  • The study found that OGG1-deficient mice had greater obesity and impaired insulin action compared to wild-type mice, underscoring OGG1's significant role in metabolism and insulin sensitivity.
  • Targeting OGG1 to mitochondria showed protective effects against HFD-induced obesity and insulin resistance, highlighting potential mechanisms that could inform future therapeutic strategies.
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Magnetoencephalography and electroencephalography (M/EEG) seed-based connectivity analysis requires the extraction of measures from regions of interest (ROI). M/EEG ROI-derived source activity can be treated in different ways. It is possible, for instance, to average each ROI's time series prior to calculating connectivity measures.

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