Publications by authors named "A Mesci"
Introduction: Patients with advanced hepatocellular carcinoma (HCC) and macrovascular invasion (MVI) are recommended to receive systemic therapy according to guidelines. Stereotactic body radiotherapy (SBRT) and surgery are increasingly used in this patient population. This study compares outcomes from these local treatments.
View Article and Find Full Text PDFIntroduction: This study aimed to assess the detection rate of prostate cancer recurrence by prostate-specific member antigen positron emission tomography/computed tomography (PSMA PET/CT) with F-DCFPyL in patients with residual disease or biochemical recurrence (BCR), and its association with surgical pathology and prostate-specific antigen (PSA) kinetics.
Methods: Men from South Central Ontario enrolled in the PSMA Registry for Recurrent Prostate cancer (PREP) between April 2019 and December 2021 after radical prostatectomy (RP) and who had 1) pathologic stage N1 or persistent elevated PSA; or 2) BCR (PSA >0.10 ng/mL) where initial postoperative PSA was undetectable were included.
Article Synopsis
- A study assessed the outcomes of patients with pancreatic ductal adenocarcinoma (PDAC) who underwent different types of pancreatic surgeries between 2011 and 2023, including non-vascular resection (NVR), venous resection (VR), and arterial resection (AR).
- Findings revealed that while initial disease stage did not impact median time to recurrence (TTR) or overall survival (OS), patients who had VR experienced significantly shorter TTR and OS compared to those with NVR and AR.
- The use of chemotherapy or chemoradiation was found to enhance both TTR and OS, while AR was linked to higher 90-day mortality rates, emphasizing the importance of careful patient selection for this procedure