Publications by authors named "A Mejia Benard"
Paraneoplastic Neurologic Syndromes Associated With Merkel Cell Carcinoma.
Neurol Neuroimmunol Neuroinflamm
November 2024
Article Synopsis
- The study focuses on understanding the clinical and immunologic characteristics of patients with paraneoplastic neurologic syndromes (PNSs) linked to Merkel cell carcinoma (MCC).
- A total of 47 patients were analyzed, revealing common neurological disorders such as Lambert-Eaton myasthenic syndrome (LEMS) and encephalomyelitis, along with significant associations with specific neural antibodies.
- The findings indicate that many patients initially presented without identifiable skin tumors but had lymph node metastases, and those without a primary tumor had a lower mortality rate compared to those with identified tumors.
Health economic evaluation of topical treatments for external anogenital warts.
Ann Dermatol Venereol
September 2024
Article Synopsis
- A study was conducted to establish a treatment hierarchy for external anogenital warts (AGW) from the perspective of the French health insurance system due to the lack of current recommendations.
- Thirteen treatments were evaluated based on their cost, effectiveness at clearing AGW, and recurrence rates after three months, using podophyllotoxin 0.5% solution as the reference treatment.
- The findings indicated that podophyllotoxin 0.5% was the cheapest option, while the most cost-effective treatment was surgical excision, and the best treatment sequence was podophyllotoxin followed by 5-fluorouracil 5% cream.
Interleukin (IL)-3 has long been known for its hematopoietic properties. However, recent evidence has expanded our understanding of IL-3 function by identifying IL-3 as a critical orchestrator of inflammation in a wide array of diseases. Depending on the type of disease, the course of inflammation, the cell or the tissue involved, IL-3 promotes either pathologic inflammation or its resolution.
View Article and Find Full Text PDFIntroduction/background: Early identification of suspected stroke patients who might be eligible for a reperfusion strategy is a daily challenge in the management of patient referrals. The aim of this study was to evaluate the performance of a remote medical assessment in identifying patients eligible for endovascular therapy (EVT) while not eligible for intravenous thrombolysis (IVT), compared with a decision based on bedside clinico-radiological data.
Methods: Patients admitted to the emergency department for acute neurological symptoms lasting for less than 24h were prospectively included.
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest forms of cancer and peritoneal dissemination is one major cause for this poor prognosis. Exosomes have emerged as promising biomarkers for gastrointestinal cancers and can be found in all kinds of bodily fluids, also in peritoneal fluid (PF). This is a unique sample due to its closeness to gastrointestinal malignancies.
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