Tin contamination in sediments of Lake Zurich: source, spread, history and risk assessment.

Unlabelled: Industrial activities of a silk dyeing factory in Thalwil, on the shore of Lake Zurich, Switzerland, caused extreme Sn contamination of lake sediments. In this study, we determine the contamination source, spread, and age using a multiproxy approach. We used X-ray fluorescence spectroscopy (XRF) core scanning and further geochemical analyses to assess the contamination spreading and thickness in the sedimentary column.

The potential of ALFA-tag and tyramide-based fluorescence signal amplification to expand the CRISPR-based DNA imaging toolkit.

Understanding the spatial organization of genomes within chromatin is crucial for deciphering gene regulation. A recently developed CRISPR-dCas9-based genome labeling tool, known as CRISPR-FISH, allows efficient labeling of repetitive sequences. Unlike standard fluorescence in situ hybridization (FISH), CRISPR-FISH eliminates the need for global DNA denaturation, allowing for superior preservation of chromatin structure.

Conformational and Substitution Effects on the Donor and Reducing Strength of Tin(II) Porphyrinogens.

Meso-octaalkylcalix[4]pyrrolates are a class of redox-active porphyrinogen ligands. They have been well established in d- and f-block chemistry for over three decades but have only recently been introduced as ligands for p-block elements. Here, we present a study on the influence of meso-substituents on the redox chemistry of calix[4]pyrrolato stannate(II) dianions [2] (R=Me, Et).

The science behind the nose: correlating volatile organic compound characterisation with canine biodetection of COVID-19.

Background: The SARS-CoV-2 pandemic stimulated the advancement and research in the field of canine scent detection of COVID-19 and volatile organic compound (VOC) breath sampling. It remains unclear which VOCs are associated with positive canine alerts. This study aimed to confirm that the training aids used for COVID-19 canine scent detection were indeed releasing discriminant COVID-19 VOCs detectable and identifiable by gas chromatography (GC-MS).