Publications by authors named "A Meda"
Rapid diagnostic tests (RDTs) targeting histidine-rich protein 2 (2) are widely used for diagnosis of infections in resource-limited malaria endemic countries. However, test results are affected by deletions of the , , and flanking genes and associated negative results from rapid diagnostic devices were previously reported. Therefore, the aim of this study was to reveal the existing genetic profile of 2 and 3 genes of -infected patients in northwestern Ethiopia.
View Article and Find Full Text PDFArticle Synopsis
- Bipolar disorder is a serious mental health problem that affects people all over the world and can lead to other health issues, especially heart problems.
- People with bipolar disorder are more likely to have heart diseases and may face a higher chance of dying from them.
- It's important to learn how bipolar disorder affects the body so that we can better help those who have it stay healthy and manage their heart health.
Intensive care unit (ICU) admissions in the United States exceed 5.7 million annually, often leading to complications such as post-intensive care syndrome and high mortality rates. Among these challenges, critical illness-related corticosteroid insufficiency (CIRCI) requires emphasis due to its complex, multiple-cause pathophysiology and varied presentations.
View Article and Find Full Text PDFArticle Synopsis
- A middle-aged woman experienced chronic foot arthritis that led to a non-healing ulcer, which didn't respond to standard treatments.
- After developing neurological issues, she was treated with antitubercular medications that healed the ulcer but caused other serious complications, including cerebral tuberculoma and tuberculous meningitis.
- Despite efforts for diagnosis and treatment, she ultimately died from the complications and a likely hospital-acquired infection, underscoring the difficulties in identifying rare disease presentations in endemic regions.
Inflammatory bowel disease is a group of long-term systemic inflammatory disorders affecting the gastrointestinal tract, including Crohn's disease and ulcerative colitis, which may be associated with an increased risk of developing extraintestinal manifestations, including cardiovascular disease, thereby decreasing the quality of life. Pathophysiological changes associated with inflammatory bowel disease include alterations of the microbiome, endotoxemia, and changes to glucose and lipid metabolism. Inflammatory bowel disease patients have higher carotid intima-media thickness, lower flow-mediated dilatation, and increased carotid-femoral pulse wave velocity, which are markers of elevated cardiovascular risk.
View Article and Find Full Text PDF