Publications by authors named "A McDiarmid"
Myocardial ischaemia following COVID-19: a cardiovascular magnetic resonance study.
Int J Cardiovasc Imaging
December 2024
The pathophysiology of myocardial injury following COVID-19 remains uncertain. COVID-HEART was a prospective, multicentre study utilising cardiovascular magnetic resonance (CMR) to characterise COVID-related myocardial injury. In this pre-specified analysis, the objectives were to examine (1) the frequency of myocardial ischaemia following COVID-19, and (2) the association between ischaemia and myocardial injury.
View Article and Find Full Text PDFPurpose: The aim of the study was to determine outcomes after heart transplantation for cytomegalovirus (CMV) mismatched patients (D/R) who underwent a surveillance and preemptive therapy protocol, compared to nonmismatch patients.
Methods: A review of patient records from January 2010 to December 2020 with follow-up to October 2023 was done. The protocol consisted weekly surveillance with CMV PCR starting 4 weeks after transplant continuing up until the patient seroconverts or up to 3 months posttransplant if the patient does not seroconvert.
Article Synopsis
- The study examined the effects of myocardial injury in hospitalized COVID-19 survivors who had elevated troponin levels, using cardiac imaging and tracking health-related quality of life over 12 months.* -
- Conducted in 25 UK centers, the research involved 342 participants, finding that while some cardiovascular events occurred, overall major adverse outcomes were low after 12 months.* -
- Results showed slight improvements in heart function and quality of life after 6 months, with no evidence of ongoing myocardial inflammation or progression of heart injury.*
Alzheimer's disease accounts for 60-70% of dementia cases. Current treatments are inadequate and there is a need to develop new approaches to drug discovery. Recently, in cancer, morphological profiling has been used in combination with high-throughput screening of small-molecule libraries in human cells .
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