Publications by authors named "A Mazon"
: Hydrolysed rice formula (HRF) is tolerated by >90% of children with cow's milk protein allergy (CMPA). However, concerns have been raised about potential suboptimal growth in infants fed HRF compared to those fed an extensively hydrolysed milk protein formula (eHF). : To compare growth, safety and tolerance acquisition in infants with CMPA when fed HRF versus eHF.
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- - The development of the CompOsite iNdexes For Response in asthMa (CONFiRM) aimed to create patient-centered tools that measure responses to biologics for severe asthma in both adults and children, integrating clinical data and quality of life (QoL) indicators.
- - Experts and patients collaborated to identify significant outcome changes and devised CONFiRM scores, which demonstrated high levels of agreement on key factors, with patients emphasizing the importance of quality of life more than healthcare professionals did.
- - The CONFiRM scores effectively measure treatment response, with strong validity metrics indicating their reliability, and they facilitate a comprehensive assessment of biologics’ effectiveness; further studies are required for prospective validation.
Background: Pollen allergy poses a significant health and economic burden in Europe. Disease patterns are relatively homogeneous within Central and Northern European countries. However, no study broadly assessed the features of seasonal allergic rhinitis (SAR) across different Southern European countries with a standardized approach.
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- PM-allergoids are new vaccines designed to target dendritic cells and induce Treg cells, with this study focusing on their safety and optimal dosage for treating house dust mite allergies in humans.
- In a clinical trial with 196 participants, doses of PM-HDM were compared against placebos using various administration routes (subcutaneous and sublingual) over four months, measuring key outcomes like nasal provocation tests and symptom scores.
- Results showed that PM-HDM was safe, with significant improvements in allergy symptoms observed at higher doses, particularly at 3000 mTU for sublingual administration and 5000 mTU for subcutaneous administration.