- There has been a notable rise in assisted reproductive therapies (ARTs), enabling many infertile couples to conceive, but these techniques may also lead to epigenetic risks affecting the health of gametes and embryos, with potential long-term consequences.
- Research has been conducted to understand the molecular mechanisms behind these ART-induced epigenetic changes using human and animal models, while highlighting the ethical responsibilities of researchers and embryologists regarding the perceived unnaturalness of ART procedures.
- The discussion includes the moral implications of human embryo research, the ethical use of model systems to study embryogenesis, and the controversial 14-day culture limit for human embryos, suggesting that scientific inquiry should continue as long as ethical boundaries are respected.