Publications by authors named "A Maurer"
Over the past decade, prostate-specific membrane antigen positron emission tomography (PSMA-PET) has revolutionized prostate cancer (PCa) imaging, offering greater sensitivity and specificity compared to conventional imaging modalities such as CT, MRI, and bone scintigraphy. PSMA-PET is particularly valuable in staging newly diagnosed patients with intermediate- and high-risk disease, detecting biochemical recurrence, and evaluating metastatic cases. By utilizing radiotracers that accumulate specifically in PSMA-expressing cells, even small metastases can be detected, offering a detailed assessment of cancer extent and enabling more targeted diagnostic evaluations.
View Article and Find Full Text PDFConsiderations and Indications for Gastric Emptying Scintigraphy in Lung Transplant Patients.
Asia Ocean J Nucl Med Biol
January 2025
Objectives: Gastroparesis is a complication following lung transplantation. This study aimed to assess the prevalence of gastroparesis in patients with lung transplants undergoing solid phase gastric emptying scintigraphy (GES). Specifically, we investigated which type of lung transplant is more susceptible to gastroparesis and whether timing of GES post-transplantation impacts diagnosis of severe gastroparesis.
View Article and Find Full Text PDFWe report a case of a 33-year-old man with epilepsy and equivocal EEG, MRI signs of mesiotemporal sclerosis, and nondiagnostic standard FDG-PET imaging. The patient underwent repeat FDG-PET/MRI to clarify the sidedness of the epileptogenic focus and to confirm the suspected MTS. The standard PET reconstruction using block sequential regularized expectation maximization failed to provide evidence of a clear epileptogenic focus.
View Article and Find Full Text PDFArticle Synopsis
- This study aimed to explore how different stomach shapes observed in gastric emptying scintigraphy (GES) relate to gastric emptying speeds, body weight, and GI symptoms.
- Researchers reviewed 397 GES studies, identifying five stomach shapes: crescentic, J-shaped, reversed-L, cylindrical, and bag-like, with crescentic being the most common.
- Findings revealed that crescentic stomachs had the highest body mass index (BMI), while bag-like stomachs showed the slowest gastric emptying and more severe regurgitation and heartburn symptoms.
Article Synopsis
- The text discusses the challenge of identifying somatic variants through single-cell RNA sequencing (scRNA-seq) due to issues like low transcript reads and protocol biases, which can miss critical genetic information.
- It introduces SIGURD (SIngle cell level Genotyping Using scRNA Data), an R-based tool designed to analyze scRNA-seq data by combining somatic and mitochondrial variants for more effective clonal analysis.
- SIGURD enables researchers to assess clonal relationships, gene expression changes, and how these variants relate to specific cell populations, as demonstrated through its application on cells from patients with myeloproliferative neoplasms.