Publications by authors named "A Mattuizzi"
Chronic histiocytic intervillositis of unknown origin (CHI) is a rare placental disorder associated with adverse pregnancy outcomes, frequent recurrence, and a lack of effective preventive strategies. Recent insights indicate a potential link between CHI-associated inflammatory lesions and the inflammasome pathway, suggesting innovative therapeutic avenues. Here we show a potential role of the inflammasome pathway in CHI through comprehensive transcriptomic analysis of grade 2 or 3 histopathologic CHI samples, paired with placental controls.
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- The study aimed to find ways to lower maternal and neonatal health issues linked to preeclampsia by reviewing literature and assessing the quality of evidence using the GRADE® method and PICO format.* -
- The findings indicated that while encouraging physical activity during pregnancy is strongly recommended to decrease preeclampsia risk, broader definitions for preeclampsia and early screening with aspirin are not recommended due to low levels of evidence.* -
- A consensus was reached among reviewers on all evaluated questions, but for women with preexisting health conditions, the evidence was insufficient to determine the effectiveness of aspirin in reducing risks associated with preeclampsia.*
Our aim was to identify factors associated with shoulder dystocia following an attempted operative vaginal delivery (aOVD) in a prospective cohort study and to evaluate whether these factors can be used to accurately predict shoulder dystocia by building a score of shoulder dystocia risk. This was a planned secondary analysis of a prospective cohort study of deliveries with aOVD at term from 2008-2013. Cases were defined as women with shoulder dystocia following an aOVD defined as a delivery that requires additional obstetric maneuvers following failure of gentle downward traction on the fetal head to effect delivery of the shoulders.
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- This study compares outcomes for women with low-lying placenta who either chose a trial of labor or an elective cesarean delivery, focusing on severe postpartum hemorrhage and maternal/neonatal morbidity.
- Conducted in France from 2007-2012, it involved 171 women out of 128,233 births, with similar rates of severe postpartum hemorrhage and morbidity between both delivery modes.
- The findings suggest that a trial of labor may be safe for women with an internal os distance of 11-20 mm after 35 weeks, although those with a distance of 1-10 mm showed lower rates of vaginal delivery.
Uterine-sparing surgical procedures to control postpartum hemorrhage.
Am J Obstet Gynecol
March 2024
Postpartum hemorrhage remains one of the principal causes of maternal mortality in the United States and throughout the world. Its management, which must be multidisciplinary (obstetrics, midwifery, anesthesiology, interventional radiology, and nursing), depends on the speed of both diagnosis and implementation of medical and surgical treatment to control the hemorrhage. The aim of this work is to describe the various techniques of vessel ligation and of uterine compression for controlling and treating severe hemorrhage, and to present the advantages and disadvantages of each.
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