Daily topical application of chlorhexidine gluconate to the skin in dogs and its impact on skin barriers and cytotoxicity.

In recent years, the importance of using local disinfectants instead of systemic antibiotics for the treatment of infectious skin diseases to prevent the emergence of resistant bacteria has become widely recognized. Chlorhexidine gluconate (CHG) is commonly used in veterinary antibacterial shampoos; however, the daily topical application of diluted CHG solutions has also been adopted. Despite its widespread use, few studies have investigated the effects of CHG on the canine skin barrier.

Alveolar Mucosa-Switching Technique for Augmentation of the Attached Immobile Mucosa.

In cases with a highly positioned mucogingival junction, an apically positioned flap in combination with palatal-mucosa grafting is commonly performed to deepen the sulcus. However, we believe that immobilizing the mucosa is more important than merely deepening it; thus, we developed a simple method based on the characteristics of its components. Elastic fiber should be replaced by collagen fiber.

Targeting Tumor Endothelial Cells by EGCG Using Specific Liposome Delivery System Inhibits Vascular Inflammation and Thrombosis.

Background: Inflammation is one of the hallmarks of cancer and is associated with tumor growth. Tumor endothelial cells (TECs) demonstrate inflamed phenotypes. Endothelial inflammation initiates thrombus formation, which is the second cause of cancer-related deaths.