Induction of defence response in peanut elicited by sp. CHEP5: A biological strategy for control of smut disease caused by in the field.

Peanut is susceptible to many diseases; among them, peanut smut disease caused by is the most damaging, causing yield losses of 30%. Fungicide treatment is not effective to control this disease. In this scenario, biological control would be an alternative to diminish the disease.

New Insights into the Exosome-Induced Migration of Uveal Melanoma Cells and the Pre-Metastatic Niche Formation in the Liver.

UM is an aggressive intraocular tumor characterized by high plasticity and a propensity to metastasize in the liver. However, the underlying mechanisms governing liver tropism remain poorly understood. Given the emerging significance of exosomes, we sought to investigate the contribution of UM-derived exosomes to specific steps of the metastatic process.

[Translated article] Changes in the Location of Cutaneous Melanoma Over the Past 30 Years. A Retrospective Observational Study.

Background: The location of cutaneous melanoma is associated with photoexposure.

Objectives: To retrospectively analyze changes in the location of cutaneous melanoma over the past 30 years.

Patients And Methods: All patients treated at our hospital for cutaneous melanoma from 1988 through 2017 were prospectively collected.

PRRX1 silencing is required for metastatic outgrowth in melanoma and is an independent prognostic of reduced survival in patients.

Paired related homeobox 1 (PRRX1) is an inducer of epithelial-to-mesenchymal transition (EMT) in different types of cancer cells. We detected low PRRX1 expression in nevus but increased levels in primary human melanoma and cell lines carrying the BRAF mutation. High expression of PRRX1 correlates with invasiveness and enrichment of genes belonging to the EMT programme.

Changes in the Location of Cutaneous Melanoma Over the Past 30 Years. A Retrospective Observational Study.

Background: The location of cutaneous melanoma is associated with photoexposure.

Objectives: To retrospectively analyze changes in the location of cutaneous melanoma over the past 30 years.

Patients And Methods: All patients treated at our hospital for cutaneous melanoma from 1988 through 2017 were prospectively collected.