Application of Phage Therapy in a Case of a Chronic Hip-Prosthetic Joint Infection due to : An Italian Real-Life Experience and Analysis.

Background: Prosthetic joint infection (PJI) caused by represents a severe complication in orthopedic surgery. We report the case of a patient with chronic PJI from successfully treated with personalized phage therapy (PT) in combination with meropenem.

Methods: A 62-year-old woman was affected by a chronic right hip prosthesis infection caused by since 2016 .

Phage-Based Control of Methicillin Resistant in a Model of Implant-Associated Infection.

implant-associated infections are difficult to treat because of the ability of bacteria to form biofilm on medical devices. Here, the efficacy of Sb-1 to control or prevent colonization on medical foreign bodies was investigated in a larval infection model. For colonization control assays, sterile K-wires were implanted into larva prolegs.

Multilocus Genotyping Reveals New Molecular Markers for Differentiating Distinct Genetic Lineages among " Phytoplasma Solani" Strains Associated with Grapevine Bois Noir.

Grapevine Bois noir (BN) is associated with infection by " Phytoplasma solani" (CaPsol). In this study, an array of CaPsol strains was identified from 142 symptomatic grapevines in vineyards of northern, central, and southern Italy and North Macedonia. Molecular typing of the CaPsol strains was carried out by analysis of genes encoding 16S rRNA and translation elongation factor EF-Tu, as well as eight other previously uncharacterized genomic fragments.

Proposal of A New Bois Noir Epidemiological Pattern Related to ' Phytoplasma Solani' Strains Characterized by A Possible Moderate Virulence in Tuscany.

Bois noir (BN), associated with ' Phytoplasma solani' (CaPsol), is the most widespread disease of the grapevine yellows complex worldwide. In this work, BN epidemiology was investigated in a case study vineyard where an unusual CaPsol strain, previously detected only in other host plants, was found to be prevalent in grapevine. Experimental activities included: symptom observation; sampling of symptomatic vines, Auchenorrhyncha specimens, and weeds; molecular detection and typing of CaPsol strains; statistical analyses for determining possible relationships between CaPsol relative concentration, strain type, and symptom severity.

Biochemical Changes in Leaves of cv. Sangiovese Infected by Bois Noir Phytoplasma.

Bois noir is a disease associated with the presence of phytoplasma ' Phytoplasma solani' belonging to the Stolbur group (subgroup 16SrXII-A), which has a heavy economic impact on grapevines. This study focused on the changes induced by phytoplasma in terms of the profile and amount of secondary metabolites synthesized in the phenylpropanoid pathway in leaves of L. red-berried cultivar Sangiovese.