Publications by authors named "A Masseau"
Article Synopsis
- * A study analyzed immune cells from 41 male Fabry patients and 20 controls, revealing that FD patients show higher expression of specific markers (CD27 and CD28) in certain T cells, which correlates with the levels of harmful lipids (lysoGb3 and Gb3) in the blood.
- * Treatment with agalsidase beta was found to increase Natural Killer cell proportions, suggesting potential new biomarker correlations that could enhance understanding and management of Fabry disease.
Background: In many countries, nitrous oxide is used in a gas mixture (EMONO) for short-term analgesia. Cases of addiction, with significant misuse, have been reported in hospitalized patients. Patients suffering from sickle cell disease (SCD) could represent a high-risk population for substance use disorder (SUD) due to their significant pain crisis and repeated use of EMONO.
View Article and Find Full Text PDFBackground: IgG4-related kidney disease is a major manifestation of IgG4-related disease, a systemic fibroinflammatory disorder. However, the clinical and prognostic kidney-related factors in patients with IgG4-related kidney disease are insufficiently defined.
Methods: We conducted an observational cohort study using data from 35 sites in two European countries.
Article Synopsis
- A study was conducted with 180 pregnant women and 168 nonpregnant women with immune thrombocytopenia (ITP) to assess the risks of ITP worsening during pregnancy and neonatal ITP (NITP).
- The findings showed that while pregnant women with ITP had a higher likelihood of severe thrombocytopenia recurrence and treatment changes, the overall risk of severe bleeding did not differ from nonpregnant women.
- NITP was identified in 14% of neonates, particularly linked to a mother's past history of NITP and low platelet counts close to delivery, providing valuable insights for advising women with ITP.
Article Synopsis
- Hereditary angioedema (HAE) is a serious condition causing unpredictable swelling attacks, and over the past decade, new treatments for long-term prophylaxis (LTP) have emerged based on a better understanding of its biology.
- A study conducted in France in 2020 surveyed physicians from 25 expert centers about their practices, treatments, and the unmet needs of HAE patients; ultimately focusing on 20 centers with active patient files.
- Of the 714 patients with C1 inhibitor deficiency, 59.2% were on LTP, but many still faced unmet needs related to treatment tolerability, efficacy, and cost; physicians expressed a desire for more effective, better-tolerated, and affordable therapies